The Activities of Zinc and Magnesium Among Alcohol Dependence Syndrome Patients: A Case-Control Study From a Tertiary Care Teaching Hospital in South India

Earlier research suggests that Mg treatment may help to normalize elevated enzyme activities and some other clinically relevant parameters among alcoholics but the evidence is weak. All of the above can be eaten to improve magnesium levels and offset the adverse effects of a deficiency. It’s important to replenish lost magnesium because many of us don’t get enough of it in our diets even before drinking alcohol. Add a night on the tiles and the loss of this essential mineral can play havoc with body, mind and spirit.

Measures were assessed for the past 90 days and included total drinks (TD90), number of drinking days (NDD90), number of non-drinking days (NNDD90), average drinking per drinking days (AvgDPD90) and heavy drinking days (HDD90). We also used the “Controlling Nutritional Status Test” (CONUT) test to establish nutritional status (Fukushima et al., 2011). That not more than 16.6% of all Mg tablets were returned unused in the Mg treatment group suggests reasonably good compliance and that possible side-effects of Mg did not interfere with the treatment. After controlling for unused Mg tablets and other factors that might have had an effect on the Mg levels a significant association between Mg treatment and serum Mg levels was found.

Does drinking alcohol affect magnesium levels?

The goal of our review was to determine whether magnesium supplementation prevents or treats AWS in adults. Our review of four trials covering 317 participants determined that there is not enough evidence about the benefits or harms of using magnesium supplements to prevent or treat AWS in adults. Alcohol causes a loss of electrolytes from the body, particularly of magnesium. Urinary loss of magnesium is common in alcoholics and particularly those who drink regularly. Although definitive studies are missing, individuals who consider themselves “light drinkers” can also have a magnesium deficiency from alcoholism. If you struggle to consume a magnesium-rich diet, consider supplementation!

Pre- and post-treatment plasma lactate in the context of low circulating serum magnesium. Male or non-pregnant or breastfeeding females ≥ 18 years of age who were capable of giving informed consent and confirmed to be experiencing alcohol withdrawal syndrome (AWS) were approached for trial participation. We found no study that measured all of the identified primary outcomes and met the objectives of this review. Only one trial measured clinical symptoms of seizure, delirium tremens or components of the Clinical Institute Withdrawal Assessment for Alcohol (CIWA) score. A single outcome (handgrip strength) in three trials (113 people), was amenable to meta-analysis.

Association of serum magnesium and drinking markers

There’s no solid medical evidence to conclusively prove it’s a cure-all, but it definitely can’t do any harm. Magnesium plays a valuable role in both mental and physical wellbeing, so it makes sense to replenish lost supplies after a heavy night. A magnesium blood test is used to check the level of magnesium in your blood. Levels that are too low are known as hypomagnesemia or magnesium deficiency. This is more common than levels that are too high, which is called hypermagnesemia.

For example, every time you drink a glass of wine you’ll lose an additional 120ml of water. While all that flushing can help rid the body of toxins, it also loses https://www.excel-medical.com/5-tips-to-consider-when-choosing-a-sober-living-house/ a lot of the good stuff too, including magnesium. The information on this site should not be used as a substitute for professional medical care or advice.

Side effects

All samples from any given patient were assayed in a single batch for each of the analytes to minimize inter-batch analytic variation23. Interestingly, magnesium (Mg2+) is required for optimal absorption of thiamine from the gut, activation of free thiamine to active phosphorylated form (thiamine diphosphate (TDP)) and optimum activity of TDP dependent enzymes16. This biochemical interdependence has been understood for decades, however only one small study has examined the in vivo effect of concomitant administration of thiamine with magnesium17.

• Magnesium has an indirect antithrombotic effect upon platelets and endothelial function.
• There’s no solid medical evidence to conclusively prove it’s a cure-all, but it definitely can’t do any harm.
• Females showed lower magnesium levels compared to the males in GR.2, although there was no statistical difference.

Whole blood EDTA samples for thiamine diphosphate measurement were frozen at − 70 °C and analyzed within ten days of being drawn. Trial samples for measurement of ETKA and erythrocyte magnesium were centrifuged (500G for 10 min), and plasma was carefully removed. Both the separated plasma and packed erythrocytes were stored at − 70 °C until analysis.

Alcohol consumption within recommended limits is unlikely to have such an impact. Properly recovering from a hangover requires care for the gut by fortifying it not only with the key electrolytes, but also by soothing it with prebiotics to improve gut health. Using NUTRIENT CO-TRANSFER TECHNOLOGY (NCT)™, we combined a complex oligosaccharide called 2’-fucosyllactose (2’-FL) with the MAGNAK electrolyte formula to create a gut health drink for rehydration.